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Margareta Wallin Peterson

Professor, Zoophysiology

Tel: 46(0)31-786 36 74 |  margareta.wallin@gu.se

Research interests

My research focused during many years on tubulin and microtubule-associated proteins isolated from higher and lower vertebrates. Of particular interest has the reason for cold-adaptation of microtubules in cold-water living animals been and several different morphological, immunological and biochemical methods have been used. During those studies we learned how to culture fish cells and study the cytoskeleton in live or fixed cells. Of special interest became fish and later also frog melanophores; cells that are involved in animal colour change. We focused on cellular mechanisms for intracellular transport of pigment granula along microtubules and microfilaments within these cells, but also how the pigment granula are transferred to other skin cells. The intracellular transport process is active, rapid and ATP-dependent and is performed with three different motor proteins; kinesin, dynein and myosin-V. Several studies were performed to increase our knowledge how the transport is regulated to either aggregate all pigment granula in the cell center (the animal becomes pale) or to disperse them throughout the cell to darken the animal. We have written several review articles on the topic of colour change in animals, the role of melanophores/melanocytes and the use of these cells for e.g. screening and toxicological studies. The latter is especially interesting since microtubules and microfilaments are of utmost importance for many cellular processes such as cell division, cell morphology, intracellular transport and cell movement.

Recently, we have therefore taking part in studies of toxicological effects of different pharmaceutical and xenobiotical substances on microtubules and microfilaments in cultured cells in collaboration with professor Malin Celander and her research group. We have also started a collaboration ass. Professor Joachim Sturve as well as professor Sofia Svedhem and her group at Chalmers in Gothenburg to look upon effects of different nanoparticles on cultured cells and the cytoskeleton.

 

 

 

Microtubules

 

Pigment Granula

Assignments

Deputy vice-chancellor, University of Gothenburg 2012-2015
Chairman for the Holding company at University of Gothenburg
Chairman for the steering-group of the Institute for Innovation and Social Change at Univerity of Gothenburg
Board member of the steering-group for Jonsered Manor
Vice chairman for the Jonsered Foundation
Project leader for Vision2020 - Medicinareberget
Vice chairman for Innovation Office Westt
Vice chairman for the board of Nordens Ark
Board member of Universeum AB
Board member of Aarhus University, Danmark
Board member of Jönköping University
Member of the KK-foundation expert group
Member of the Wilhelm and Martina Lundgrens science foundation

Project

The web-journal Bioscience explained (www.bioscience-explained.org) – Swedish and English journal for school teachers with special emphasise on practicals and reviews. Run in collaboration with the National Centre for Biotechnology Education, Reading University, England.

Bioscience Explained
 

 

 

 

 

 

 

 

 

 

Publications

2018

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1988

Margareta Wallin Peterson

Contact Information

Department of Biological and Environmental Sciences

Box 463, SE- 405 30 Göteborg

Visiting Address:
Medicinaregatan 18

Phone:
+46 (0)31- 786 00 00

Fax:
+ 46 (0)31- 41 67 29

Page Manager: Sven Toresson|Last update: 8/22/2013
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